Articles

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105 results found
Article

Thymic tumor (staging)

The thymic tumor staging using the TNM staging system only applies to the epithelial types including thymoma, thymic carcinoma, and neuroendocrine tumors of the thymus. It does not apply to thymic sarcoma, primary thymic lymphoma or other rare tumors. This staging system is based upon recommend...
Article

Visceral pleural invasion

Visceral pleural invasion is a feature that can be seen in lung cancers. It is defined as tumor extension beyond the elastic layer of the visceral pleura, and in some cases may result in a cancer crossing a fissure to invade an adjacent lobe of the lung. It is considered an aggressive sign and o...
Article

Iannetti classification of orbital invasion

The Iannetti classification grades orbital invasion by ethmoido-orbital tumors, such as adenocarcinoma, squamous cell carcinoma, adenoid cystic carcinoma, undifferentiated carcinoma, sarcoma, or olfactory neuroblastoma. Classification grade I: erosion or destruction of the orbital medial wall ...
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Esophageal and esophagogastric junction neuroendocrine tumor (staging)

Esophageal and esophagogastric junction neuroendocrine tumor staging refers to TNM staging of epithelial cancers other than the squamous cell carcinoma and adenocarcinoma groups located in the esophagus or esophagogastric junction (including tumors whose center is within the proximal 2 cm of the...
Article

Hepatoblastoma (staging)

As expected there are a number of different staging systems for hepatoblastoma. Staging PRETEXT grouping system of pediatric liver tumors not specific to hepatoblastoma; used in all pediatric liver tumors Intergroup staging system specific for hepatoblastoma (see below) Intergroup staging ...
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Skip metastases to the axillary lymph nodes in breast cancer

Skip metastases to the axillary lymph nodes in breast cancer refer to the uncommon phenomenon in which metastases do not follow the conventional stepwise pattern from level I to level II, to level III (infraclavicular), to the supraclavicular fossa, and or internal jugular chain 1-6,9. Terminol...
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Pediatric liver tumor staging (PRETEXT grouping system)

The PRETEXT system proposed by the International Childhood Liver Tumors Strategy Group (previously called Société Internationale d’Oncologie Pédiatrique - Epithelial Liver Tumor Study Group - SIOPEL) aims for staging and risk stratification of liver tumors at diagnosis.  It is used to describe ...
Article

Small cell lung cancer (staging) (historical)

Previously, small cell lung cancer (SCLC) was not staged in the same manner as non-small cell lung cancer (NSCLC), but since 2013 both are staged using the IASLC (International Association for the Study of Lung Cancer) lung cancer staging system.  The idea behind a different staging system for ...
Article

Gleason score

The histological grading of prostate cancer has undergone many revisions, and for many years the primary system was the Gleason score, itself derived from the Gleason grade. In 2014, the Grade Group was introduced, and care must be taken to not confuse this with the Gleason grade. The Gleason g...
Article

Dukes staging system for colorectal cancer

The Dukes staging system is a classification system for colorectal cancer. This system is now mainly of historical interest as it has largely been replaced by the TNM staging system. It is not recommended for clinical practice. Dukes A: invasion into but not through the bowel wall (90% 5-year s...
Article

ECOG performance status

The ECOG performance status, often just called the performance status (PS), is a scale used to assess how a patient's disease is progressing, assess how the disease affects the daily living abilities of the patient, and determine appropriate treatment and prognosis (it is one of the three compon...
Article

Lung cancer (staging - IASLC 8th edition)

The IASLC (International Association for the Study of Lung Cancer) 8th edition lung cancer staging system was introduced in 2016 and supersedes the IASLC 7th edition. It is a TNM staging system. Standard-of-care lung cancer staging ideally should be performed in a multidisciplinary meeting usin...
Article

Juvenile nasopharyngeal angiofibromas (staging)

Staging of juvenile nasopharyngeal angiofibromas is performed with cross-sectional imaging and relies on the identification of local tumor extent, and invasion of adjacent spaces. For a discussion of this entity please refer to the parent article: juvenile nasopharyngeal angiofibroma.  The stag...
Article

iRANO criteria

The immunotherapy response assessment for neuro-oncology (iRANO) criteria have been developed as a modification of RANO criteria to address the challenges of emerging novel immunotherapy for high-grade gliomas 1. Although these criteria have been primarily for the purposes of standardizing asses...
Article

Akeret staging of neuroepithelial tumors

The Akeret or anatomical staging of neuroepithelial tumors adheres loosely to the general scheme underlying AJCC TNM staging. Like other cancer staging systems, it assists in estimating the individual prognosis, in tailoring patient-specific therapy and surveillance, and in improving the compara...
Article

Distal cholangiocarcinoma (staging)

Distal cholangiocarcinoma staging is defined according to the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. These criteria apply to cancer...
Article

Cancer staging list

Cancer staging involves a number of systems to help direct treatment and aid prognosis. The AJCC TNM staging schema is the most common, but other systems are used for specific malignancies or body parts. Breast breast cancer staging Chest lung cancer staging malignant pleural mesothelioma s...
Article

Rhabdomyosarcoma (staging)

Rhabdomyosarcoma staging is based on the Lawrence/Gehan staging system, which comprises of a combination of pretreatment staging and postoperative clinical grouping. Stage stage I: orbit, eyelid, head and neck (excluding parameningeal), genitourinary (non-bladder, non-prostate), N0 or 1, M0 s...
Article

Rectal cancer (staging)

Staging of rectal cancer uses the TNM staging system and strongly predicts the success, and rate, of local recurrence following rectal cancer resection. MRI is the modality of choice for the staging of rectal cancer, to guide surgical and non-surgical management options. MRI is used at diagnosis...
Article

Deauville five-point scale

The Deauville five-point scale (Deauville 5PS) is an internationally-recommended scale for routine clinical reporting and clinical trials using FDG PET-CT in the initial staging and assessment of treatment response in Hodgkin lymphoma (HL) and certain types of non-Hodgkin lymphomas (NHL).  Incl...

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