Articles

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746 results found
Article

Very bizarre generalized lesions of bone (differential)

Very bizarre generalized lesions of bone tend to make you exclaim "Oh my! What is going here?"  Although there are numerous potential causes, in this situation it is worth thinking of a number of entities: skeletal dysplasias and metabolic diseases Paget disease fibrous dysplasia phakomatose...
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Bilateral axillary lymphadenopathy (differential)

Bilateral axillary lymphadenopathy can result from a number of causes and generally implies a systemic process. They include: autoimmune diseases, e.g.: rheumatoid arthritis scleroderma dermatomyositis 5 systemic lupus erythematosus (SLE) psoriasis Sjögren syndrome lymphoma leukemia di...
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Multicentric breast cancer

A multicentric breast cancer is a term given to a breast cancer where there are two or more breast cancers separated by normal breast tissue (often taken as 5 cm of separation 4). It is related to but distinct from the term multifocal breast cancer. At a pathological level It can also mean 2 t...
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Long bone metaphyseal cupping (differential)

Long bone metaphyseal cupping is most likely due to the local oligemia from thrombosis in the terminal epiphyseal arteries to the epiphyseal plate, induced by prolonged regional immobilization 7.  The differential diagnosis of long bone metaphyseal cupping includes:  Common normal variant re...
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Diffuse pulmonary nodules

Diffuse pulmonary nodules are usually seen as multiple pulmonary nodular opacifications on a HRCT chest scan. They can signify disease processes affecting either the interstitium or the airspace. They can range from a few millimeters to up to 1 cm and when very small and numerous there can be so...
Article

Patellar tumors

Patellar tumors are extremely rare. They can be either benign or malignant primary bone tumors, or metastases.  Epidemiology Patellar tumors represent just 0.1% of all primary bone tumors 1.  Clinical presentation Patients may present with anterior knee pain and/or a palpable mass 1,3. Path...
Article

Basal ganglia T2 hypointensity

Basal ganglia T2 hypointensities can be caused by any of the following and is commonly remembered using the mnemonic ChOMP. childhood hypoxia old age multiple sclerosis Parkinson disease: more in globus pallidus Parkinson-plus syndrome: more in putamen deoxyhemoglobin of hemorrhage hemosi...
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Focal calvarial thinning

Focal calvarial thinning can result from a number of causes. They include: bilateral thinning of the parietal bones (normal variant) most common arachnoid cyst mega cisterna magna peripherally located tumors (e.g. oligodendroglioma) See also calvarial thinning calvarial thickening
Article

Gastric outlet obstruction

Gastric outlet obstruction, also known as pyloric obstruction, occurs when a disease or condition blocks the normal emptying of the stomach. Pathology Etiology Gastric outlet obstruction can be due to malignant or benign causes. Malignant adenocarcinoma (second most common 4) GIST lymphom...
Article

Enteritis

Enteritis (plural: enteritides) refers to inflammation of the small bowel. When associated with inflammation of the stomach, the term gastroenteritis is used which is usually caused by infection. Pathology Etiology infection infective enteritis eosinophilic enteritis ischemia inflammatory...
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Generalized increased bone density in children

The causes of generalized increased bone density in pediatric patients can be divided according to a broad category of causes: skeletal dysplasias osteopetrosis pyknodysostosis metabolic renal osteodystrophy poisoning lead dense metaphyseal bands cortex and flat bones may also be slight...
Article

Ascending aorta dilatation

Dilatation of the ascending aorta is a common finding in the elderly but unusual in younger patients. Pathology In adults, an ascending aortic diameter greater than 4 cm is considered to indicate dilatation 4. Aneurysmal dilatation is considered when the ascending aortic diameter reaches or ex...
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Bilateral hypertranslucent hemithoraces

Bilateral hypertranslucent hemithoraces is the presence of decreased density of the hemithoraces bilaterally on a plain chest radiograph. This hypertranslucency, a.k.a. hyperlucency, may be focal or diffuse 1.  Also see unilateral hypertranslucent hemithorax.  Focal pulmonary bullae localize...
Article

Bone surface lesions

Bone surface lesions refer to all neoplastic or neoplastic-like lesions arising from the bone surface (cortex, periosteum, and parosteal fibrous tissues) and developing outside of the bone medullary canal. Neoplastic fat-containing matrix parosteal lipoma parosteal osteoliposarcoma 2 bone m...
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Apical chest mass

Apical chest masses are often important and may be missed, especially when examined with a plain chest radiograph. It is always recommended to perform a targeted assessment of the apices of the lungs during a chest x-ray; they are one of the classic review areas. Pathology Etiology Commonly a...
Article

Echogenic fetal lung lesions

Echogenic fetal lung lesions on antenatal ultrasound can be detected in a number of situations. They include: Airway obstructions: lung are often enlarged and echogenic bilaterally congenital high airways obstruction syndrome (CHAOS) tracheal atresia congenital tracheal stenosis laryngeal a...
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Flowing ossifications

Flowing ossifications are seen in diffuse idiopathic skeletal hyperostosis (DISH). They are defined as heterotopic ossifications involving the anterior longitudinal ligament, paraspinal connective tissues and annulus fibrosus of at least four contiguous vertebral bodies and are originally descri...
Article

Fluid-fluid level containing bone lesions

Fluid-fluid level containing bone lesions are best seen on MRI, although with narrow window width they can also be appreciated on CT. Epidemiology Their prevalence is estimated at ~3% of bone and soft tissue tumors 1. Differential diagnosis Their presence is non-specific, as they are seen in...
Article

Fetal ventriculomegaly (differential)

Fetal ventriculomegaly (ventricle width >10 mm) is an important finding in itself and it is also associated with other central nervous system abnormalities. For more information, see the main article fetal ventriculomegaly. Differential diagnosis Fetal ventriculomegaly can be thought of in ter...
Article

Cerebral cortical restricted diffusion

Cerebral cortical restricted diffusion, also known as gyriform restricted diffusion, cortical ribboning or cortical ribbon sign, refers to curvilinear hyperintense signal involving the cerebral cortex on DWI images with a corresponding low signal on ADC images. Causes include the following diso...

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