Adrenal calcification
Dr Yuranga Weerakkody and Dr Frank Gaillard et al.
Adrenal calcification is not a rare finding in healthy asymptomatic people, and is usually the result of previous haemorrhage, or tuberculosis. Addison's disease patients only occasionally have calcification.
Pathology
Causes
Haemorrhage
- sepsis : Waterhouse-Friderichsen syndrome
- blunt abdominal trauma
- neonatal asphyxia
- coagulopathy
- infants : calcification seen soon after haemorrhage (as early as 1 - 2 weeks)
Infection
Adrenal tumours
- adrenal metastases - especially melanoma
- neuroblastoma
- adrenal myelolipoma
- adrenal adenoma
- adrenocortical carcinoma
- pheochromocytoma
Others
-
Addison disease
- uncommon in primary Addison disease; calcification suggests an underlying cause (e.g. infection)
- Wolman disease
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