Adrenal hyperplasia
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Adrenal hyperplasia refers to nonmalignant growth (enlargement) of the adrenal glands and is a rare cause of ACTH-independent Cushing syndrome, with unilateral adrenal cortical adenomas being the commonest. 20% of Conn syndrome cases are secondary to adrenal hyperplasia. InIn diffuse hyperplasia, the limbs of the adrenal glands are >5 cm in length and >10 mm in thickness.
Pathology
Classification
Adrenal hyperplasia can be classified according to:
- inheritance
- congenital
- acquired adrenal hyperplasia
(s)
- morphology
Radiographic features
- enlarged limbs of one or both adrenal glands >10 mm thick
- normal adrenal morphology maintained
- nodular or uniform
MRI
- high lipid content and thus may demonstrate signal
drop outdropout in out-of-phase chemical shift imaging - signal
drop outdropout due to lipid content overlaps with adrenal cortical adenomas
See also
-<p><strong>Adrenal hyperplasia</strong> refers to nonmalignant growth (enlargement) of the <a href="/articles/adrenal-gland">adrenal glands</a> and is a rare cause of ACTH-independent <a href="/articles/cushing-syndrome">Cushing syndrome</a> with unilateral adrenal cortical adenomas being the commonest. 20% of <a href="/articles/conn-syndrome">Conn syndrome</a> cases are secondary to adrenal hyperplasia. In diffuse hyperplasia, the limbs of the adrenal glands are >5 cm in length and >10 mm in thickness. </p><h4>Pathology</h4><h5>Classification</h5><p>Adrenal hyperplasia can be classified according to:</p><ul>- +<p><strong>Adrenal hyperplasia</strong> refers to nonmalignant growth (enlargement) of the <a href="/articles/adrenal-gland">adrenal glands</a> and is a rare cause of ACTH-independent <a href="/articles/cushing-syndrome">Cushing syndrome</a>, with unilateral adrenal cortical adenomas being the commonest. 20% of <a href="/articles/conn-syndrome">Conn syndrome</a> cases are secondary to adrenal hyperplasia. In diffuse hyperplasia, the limbs of the adrenal glands are >5 cm in length and >10 mm in thickness. </p><h4>Pathology</h4><h5>Classification</h5><p>Adrenal hyperplasia can be classified according to:</p><ul>
-<li><a href="/articles/congenital-adrenal-hyperplasia">congenital adrenal hyperplasia</a></li>- +<li><a href="/articles/congenital-adrenal-hyperplasia">congenital adrenal hyperplasia (CAH)</a></li>
-<li>acquired adrenal hyperplasia(s)</li>- +<li>acquired adrenal hyperplasia</li>
-<li><a title="micronodular adrenal hyperplasia" href="/articles/micronodular-adrenal-hyperplasia">micronodular adrenal hyperplasia</a></li>- +<li><a href="/articles/micronodular-adrenal-hyperplasia">micronodular adrenal hyperplasia</a></li>
-<a title="Macronodular adrenal hyperplasia" href="/articles/macro-nodular-adrenal-hyperplasia-2">macronodular adrenal hyperplasia</a><ul><li><a href="/articles/adrenocorticotropin-independent-macronodular-adrenocortical-hyperplasia">adrenocorticotropin independent macronodular adrenocortical hyperplasia (AIMAH) </a></li></ul>- +<a href="/articles/macronodular-adrenal-hyperplasia-1">macronodular adrenal hyperplasia</a><ul><li><a href="/articles/adrenocorticotropin-independent-macronodular-adrenocortical-hyperplasia">adrenocorticotropin independent macronodular adrenocortical hyperplasia (AIMAH) </a></li></ul>
-<li>enlarged limbs of one or both adrenal glands >10 mm</li>- +<li>enlarged limbs of one or both adrenal glands >10 mm thick</li>
-<li>high lipid content and thus may demonstrate signal drop out in out-of-phase imaging</li>-<li>signal drop out due to lipid content overlaps with adrenal cortical adenomas</li>-</ul><h4>See also</h4><ul><li><a href="/articles/bilateral-adrenal-enlargement">bilateral adrenal enlargement</a></li></ul>- +<li>high lipid content and thus may demonstrate signal dropout in out-of-phase chemical shift imaging</li>
- +<li>signal dropout due to lipid content overlaps with adrenal cortical adenomas</li>
- +</ul><h4>See also</h4><ul><li><a href="/articles/bilateral-adrenal-gland-enlargement">bilateral adrenal enlargement</a></li></ul>
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