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Ageing blood on MRI

The imaging characteristics of blood on MRI are variable and change with the age of the blood.

In general 5 stages of haematoma evolution are recognised:

  1. hyper acute
    • intracellular oxyhaemoglobin
    • iso intense on both T1 and T2
  2. acute (1 to 2 days)
    • intracellular deoxyhaemoglobin
    • T2 signal intensity drops (T2 shortening)
    • T1 remains intermediate to long
  3. early sub acute (2 to 7 days)
    • intracellular met-haemoglobin
    • T1 signal gradually increases (T1 shortening) to become hyper intense
  4. late sub acute (7 to 14 - 28 days)
    • extracellular met-haemoglobin : over the next few weeks : as cells break down, extracellular met haemoglobin lead to an increase in T2 signal also
  5. chronic ( > 14 - 28 days)
    • periphery
      • intracellular haemosiderin
      • low on both T1 and T2
    • center
      • extracellular hemichromes
      • iso intense T1, hyper intense T2

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