Anti-neutrophil cytoplasmic antibody associated vasculitides

Last revised by Craig Hacking on 25 Jun 2020

Anti-neutrophil cytoplasmic antibody (ANCA) - associated vasculitides refer to a group of heterogeneous autoimmune diseases characterized by necrotizing vasculitides and positive ANCA titers. They are reactive to either proteinase-3 (PR3-ANCA) - cANCA or myeloperoxidase (MPO-ANCA) - pANCA. These vasculitides affect arterioles, capillaries, and venules which can involve virtually any organ with varying degrees of severity. As a general rule, the lungs and kidneys are the most commonly involved.

The conditions that fall into this group are:

See also

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.