An arachnoid granulation (also known as a Pacchionian granulation) most frequently occurs in a parasagittal location and can cause an osteolytic, sharply circumscribed lucency on a skull x-rays, or a filling defect in dural venous sinuses, which can be mistaken for dural venous thrombosis. They increase in size with age and are seen in approximately two thirds of patients.
Signal characteristics are generally those of CSF 2 with
- T1 : low signal intensity
- T2 : high signal intensity : iso to even slightly hyperintense to CSF
- FLAIR : should attenuate
- T1 C+(Gd) : no enhancement
Named after Antonio Pacchioni an Italian anatomist (1665 - 1726), who wrote extensively on the anatomy of the dura mater, published in 1705.
- 1. Antonio Pacchioni from whonamedit.com, the dictionary of medical eponyms. Antonio Pacchioni
- 2. Ikushima I, Korogi Y, Makita O et-al. MRI of arachnoid granulations within the dural sinuses using a FLAIR pulse sequence. Br J Radiol. 1999;72 (863): 1046-51. Br J Radiol (abstract) - Pubmed citation
- 3. Applied Radiology online
- 4. Rodallec MH, Krainik A, Feydy A et-al. Cerebral venous thrombosis and multidetector CT angiography: tips and tricks. Radiographics. 2006;26 Suppl 1 : S5-18. doi:10.1148/rg.26si065505 - Pubmed citation
Synonyms & Alternative Spellings
|Synonyms or Alternative Spelling||Include in Listings?|