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Bilateral adrenal enlargement

Dr MT Niknejad and Dr Frank Gaillard et al.

The differential for bilaterally enlarged adrenal glands is relatively limited:

adrenal hyperplasia
- micro nodular adrenal hyperplasia
- macro nodular adrenal hyperplasia
  - adrenocorticotropin (ACTH)-independent macronodular adrenocortical hyperplasia (AIMAH) ²
adrenal metastases
adrenal haemorrhage
adrenal involvement with granulomatous diseases
adrenal lymphoma
primary pigmented nodular adrenal dysplasia (PPNAD) : usually the glands are normal in size, but nodular. In older patients they may be enlarged ¹.

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