Bone scan is a nuclear medicine (scintigraphic) study that makes use of Technetium 99m (commonly Tc99m-methylene diphosphonate (MDP)) as the active agent.
The study has three stages which follow intravenous injection of the tracer.
- malignancy: detection and follow-up of skeletal metastases
- detection of radiographically occult fractures
- reflex sympathetic dystrophy
- hip joint prosthesis: evaluation for infection or loosening
- remove metal objects
- void immediately before study
Tracer dose and route of administration
Tc99m diphosphonate is administered intravenously, at a dose of 20 mCi.
- 2 to 5-sec images are obtained for 60 seconds after injection
- demonstrates perfusion and characterises the blood flow to a particular area
Blood pool phase
- the blood-pool image is obtained 5 min after injection
- demonstrates the blood pool, not the blood flow
- inflammation causes capillary dilatation and increased blood flow
If the study is going to be a triphasic bone scan, a third phase is added.
- the bone image is obtained 2-4 hours later
- urinary excretion has decreased the amount of the radionuclide in soft tissue
Synonyms & Alternative Spellings
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|Triphasic bone scan||✗|