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Buschke-Ollendorff syndrome

The Buschke-Ollendorff syndrome (BOS) comprises of osteopoikilosis associated with disseminated connective tissue  and cutaneous yellowish naevi, predominantly on the extremities and trunk 1-2.  

Recent genetic work has linked BOS to both isolated osteopoikilosis and melorheostosis1.

Etymology

It was first described by the follwing three people

  • Helene Ollendorff Curth : German-American dermatologist, Columbia University (1899-?)
  • Abraham Buschke : German dermatologist (1868 - 1943) 
  • Hans Theodor Schreus : German radiologist (1892 - 1970) 
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