The carcinoid syndrome refers to a spectrum of symptoms which includes flushing, diarrhea, bronchospasm, pain, and right heart failure which can occur in the context of a carcinoid tumour. The symptoms result from systemic circulation of secretory substances: serotonin, histamine etc. The presence of the carcinoid syndrome often indicates hepatic metastatic disease, usually from a primary bowel carcinoid tumour.
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