A cardiac fibroma (also known as cardiac fibromatosis, fibrous hamartoma, or fibroelastic hamartoma) represents a collection of fibroblasts interspersed among large amounts of collagen (some authors believe that this tumour is a hamartoma rather than a neoplasm).
Cardiac fibroma is a tumour that primarily affects children (most cases is detected in infants or in utero). They are the second most common benign primary cardiac tumour in children after cardiac rhabdomyoma and second commonest fetal cardiac tumour 2.
Cardiac fibromas are often associated with arrhythmias which can be a presenting feature.
There is an increased prevalence of cardiac fibromas in Gorlin syndrome.
Unlike many primary cardiac tumours, fibromas usually have no foci of cystic change, hemorrhage, or necrosis.Cardiac fibromas almost always arise in the ventricles, most commonly in the ventricular septum and left ventricular free wall.They are usually large, with a mean diameter of about 5 cm and may obliterate the ventricular cavity.
At CT, cardiac fibromas are homogeneous soft-tissue masses that may be either sharply marginated or infiltrative. Dystrophic calcification is common.
Because of their dense, fibrous nature, the tumors are usually homogeneous and hypointense on T2-weighted MR images and isointense relative to muscle on T1-weighted images.
Cardiac fibromas often demonstrate little or no contrast material enhancement.
- 1. Araoz PA, Mulvagh SL, Tazelaar HD et-al. CT and MR imaging of benign primary cardiac neoplasms with echocardiographic correlation. Radiographics. 20 (5): 1303-19. Radiographics (full text) - Pubmed citation
- 2. Kim TH, Kim YM, Han MY et-al. Perinatal sonographic diagnosis of cardiac fibroma with MR imaging correlation. AJR Am J Roentgenol. 2002;178 (3): 727-9. AJR Am J Roentgenol (full text) - Pubmed citation
Synonyms & Alternative Spellings
|Synonyms or Alternative Spelling||Include in Listings?|
|Cardiac fibrous hamartoma||✗|
|Cardiac fibroelastic hamartoma||✗|