Carney complex
The Carney complex (not to be confused with the Carney triad) is a rare form of multiple endocrine neoplasia syndromes, which is autosomal dominant in inheritance and is characterised by 1-4:
- cardiac myxoma
- often multiple
- seen in two thirds of patients with Carney complex
- skin pigmentation (blue naevi) : especially of the face, trunk, lips, and sclera
Multiple other features are also well recognised including:
- extra cardiac myxoma
- breast
- testis
- thyroid
- brain
- adrenal gland : primary pigmented nodular adrenocortical disease (PPNAD)
- pituitary adenoma
- psammomatous melanotic schwannoma
- testicular tumours
- Sertoli cell tumours : most common
