The Carney triad (not to be confused with the Carney complex) is a rare syndrome defined by the coexistence of three tumours:
- extra-adrenal paraganglioma (e.g. extra adrenal phaeochromocytoma) : initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal paragangliomas 1
- gastric gastrointestinal stromal tumors (GIST): previously known as gastric epithelioid leiomyosarcoma
- pulmonary chondroma (hamartoma)
In most cases, only 2 of the 3 tumours are present at the time of diagnosis.
It typically affects young people.
First described by J. Aidan Carney and colleagues in 1977.
- 1.Carney J A. Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence. Mayo Clin Proc. 1999 Jun;74(6):543-52. PubMed
- 2 .Carney J A, Sheps S G, Go V L, Gordon H. The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N Engl J Med. 1977;296(26):1517-8. PubMed
- 3. Felix S. Chew et.al, Imaging of Pheochromocytoma and Incidental Adrenal Lesions: Self-Assessment Module, AJR 2006; 187:S467-S469