The Carney triad (not to be confused with the Carney complex) is a rare syndrome defined by the coexistence of three tumours:
- extra-adrenal paraganglioma (e.g. extra adrenal phaeochromocytoma) : initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal paragangliomas 1
- gastric gastrointestinal stromal tumors (GIST): previously known as gastric epithelioid leiomyosarcoma
- pulmonary chondroma (hamartoma)
In most cases, only 2 of the 3 tumours are present at the time of diagnosis.
It typically affects young people.
First described by J. Aidan Carney and colleagues in 1977.
- 1. Carney JA. Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence. Mayo Clin. Proc. 1999;74 (6): 543-52. doi:10.4065/74.6.543 - Pubmed citation
- 2. Carney JA, Sheps SG, Go VL et-al. The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N. Engl. J. Med. 1977;296 (26): 1517-8. doi:10.1056/NEJM197706302962609 - Pubmed citation
- 3. Chew F, Banks K. American Journal of Roentgenology. 2006;187 (3_supplement): . doi:10.2214/AJR.06.0521