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The cerebral peduncles (also known as the cerebral crus) are the part of the midbrain that link the remainder of the brainstem to the thalami and thereby, the cerebrum. They are the most anterior structure in the midbrain and contain the large ascending and descending tracts that run to and from the cerebrum.
The peduncles form the walls of the fourth ventricle.
The substantia nigra is located within the cerebral peduncles and considered the structure that separates the cerebral crus from the tegmentum.
The term "cerebral peduncles" may be used to refer to a collective structure that includes the cerebral crus and the tegmentum together.
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