Chondrosarcoma grading allows the division of chondrosarcoma into 3 (sometimes 4) grades.
Grade 1 - low grade
- low cellularity
- mostly chondroid matrix
- little if any myxoid
- difficult to distinguish from enchondroma (see enchondroma vs. low grade chondrosarcoma for imaging distinguishing features)
Grade 2 - intermediate grade
- increased cellularity
- little chondroid matrix
- necrosis and more common prominent myxoid
Grade 3 - high grade
- highly cellular
- nuclear pleomorphism
- absent chondroid matrix
- stroma present is myxoid
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