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Chronic hypersensitivity pneumonitis

Dr Yuranga Weerakkody and Dr Yi-Jin Kuok et al.

Chronic hypersensitivity pneumonitis (CHP) refers to hypersensitivity pneumonitis where there is radiological evidence of fibrosis and represents the end-stage of repeated or persistent pneumonitis 7.

Radiographic features

HRCT chest

HRCT typically reveals centrilobular, peribronchiolar, indistinct nodular opacities, of various numbers 5.

Other features include

The presence of an extensive reticular pattern, traction bronchiectasis, and honeycombing have been shown to be closely related to the presence of histologic fibrosis in chronic HP 6.

Differential diagnosis

In some cases it may be difficult to differentiate from that of idiopathic pulmonary fibrosis 4.

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