Chronic lung disease in sickle cell anaemia
Dr Jan Frank Gerstenmaier and Dr Yuranga Weerakkody et al.
Chronic lung disease is one of the pulmonary complication that can occur with sickle cell disease.
Clinical presentation
Patients often present slow progressive decline in pulmonary function in individuals affected with HbSS. Individually usually have a preceding history of several events of acute chest syndrome of sickle cell disease.
Pathology
Established fibrotic lung changes from repeated episodes of pulmonary infective and micro-occlusive events.
Radiographic features
HRCT
May show interstitial changes with septal thickening, wedge opacities and traction bronchiectasis.
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