Classification system for midline abnormalities of the brain and skull
Dr Abhilash Sandhyala and Dr Frank Gaillard et al.
Classification systems for midline abnormalities of the brain and skull are varied and constantly changing a the underlying embryology and genetics are uncovered. A relatively simple and robust classification system is based on the location of abnormalities, always remembering that midline abnormalities often 'travel in packs'.
-
cephaloceles
- by location: cranial vault or skull base
- by content: meninges only or also contain brain tissue
- nasal region
- cerebral hemispheres
-
holoprosencephaly / septo-optic dysplasia spectrum
- septo-optic dysplasia
- lobar holoprosencephaly
- semilobar holoprosencephaly
- alobar holoprosencephaly
- middle interhemispheric variant / syntelencephaly
-
holoprosencephaly / septo-optic dysplasia spectrum
- corpus callosum
- intracranial lipoma
- cerebellum (for more details see classification system for malformations of the cerebellum)
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