This site is targeted at medical and radiology professionals, contains user contributed content, and material that may be confusing to a lay audience. Use of this site implies acceptance of our Terms of Use.

Congenital granular cell myoblastoma

Dr Abhilash Sandhyala and Dr Yuranga Weerakkody et al.

A congenital granular cell myoblastoma (also known as congenital epulis) is a very rare benign tumour which classically presents in the fetal-neonatal population.

Epidemiology

It occurs almost exclusively in females when it presents in the fetal neonatal population although no such predilection occur when it rarely presents in older children.

Pathology

It is thought to occur as a result of excessive oestrogen production from the fetal ovaries under HCG stimulation.

The histogenesis is uncertain, and proposed cells of origin include odontogenic epithelium, undifferentiated mesenchymal cells, pericytes, fibroblasts, smooth muscle cells, nerve related cells, and histiocytes.

Location

It most commonly occurs along the alveolar ridge of the maxilla although less commonly, it can also occur inrelation to the mandible.

Radiographic feautres

Antenatal ultrasound

Rarely a congetnial epulis may be detected on antenatal ultrasound as an intra-oral mass. Colour and power Doppler ultrasound examination may show marked blood flow within the tumour ⁵.

Differential diagnosis

General considerations include

This article is a stub, which means it needs more content. You can contribute to Radiopaedia.org too. Just register and edit... every little bit helps.