A useful mnemonic to remember the causes of corpus callosum hyperintensity is:
- I MADE A PHD
Mnemonic
-
I: infections (e.g. tuberculosis, varicella, rotavirus, HSV)
- M: Marchiafava-Bignami syndrome
- A: AIDS encephalopathy
- D: diffuse axonal injury and diffuse vascular injury
-
E: epilepsy
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A: autoimmune disorders: hemolytic uremic syndrome-related encephalopathy
- P: posterior reversible encephalopathy syndrome
- H: hypoglycemia
- D: demyelination (e.g. multiple sclerosis, ADEM, PML)