CSF cleft sign
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The CSF cleft sign in neuroimaging can be used to distinguish an extra-axial lesion from an intra-axial lesion and is typically used in the description of a meningioma.
Classically, the cleft was regarded as representing a thin rim of CSF between a tumour and brain parenchyma. However, it often is of high signal on FLAIR imaging (i.e. does not suppress on FLAIR) and most likely represents a non-CSF tumour-brain interface or CSF admixed with solutes, which can be thought of as 'tumour juice'
Nevertheless, it remains a good sign that a mass is extra-axial and typically consists of:
-<p>The<strong> CSF cleft sign</strong> in neuroimaging can be used to distinguish an <a href="/articles/extra-axial-1">extra-axial</a> lesion from an <a href="/articles/intra-axial-2">intra-axial</a> lesion and is typically used in the description of a <a href="/articles/meningioma">meningioma</a>.</p><p>Classically, the cleft was regarded as representing a thin rim of <a href="/articles/cerebrospinal-fluid-1">CSF</a> between a tumour and brain parenchyma. However, it often is of high signal on <a href="/articles/fluid-attenuated-inversion-recovery">FLAIR</a> imaging (i.e. does not suppress on FLAIR) and most likely represents a non-CSF tumour-brain interface or CSF admixed with solutes, which can be thought of as '<a title="Tumour juice" href="/articles/tumour-juice">tumour juice</a>'. </p><p>Nevertheless, it remains a good sign that a mass is extra-axial and typically consists of:</p><ul>- +<p>The<strong> CSF cleft sign</strong> in neuroimaging can be used to distinguish an <a href="/articles/extra-axial-1">extra-axial</a> lesion from an <a href="/articles/intra-axial-2">intra-axial</a> lesion and is typically used in the description of a <a href="/articles/meningioma">meningioma</a>.</p><p>Classically, the cleft was regarded as representing a thin rim of <a href="/articles/cerebrospinal-fluid-1">CSF</a> between a tumour and brain parenchyma. However, it often is of high signal on <a href="/articles/fluid-attenuated-inversion-recovery">FLAIR</a> imaging (i.e. does not suppress on FLAIR) and most likely represents a non-CSF tumour-brain interface or CSF admixed with solutes. </p><p>Nevertheless, it remains a good sign that a mass is extra-axial and typically consists of:</p><ul>
-</ul>- +</ul><div id="gtx-trans" style="position: absolute; left: 318px; top: 131.4px;"><div> </div></div>
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