This site is targeted at medical and radiology professionals, contains user contributed content, and material that may be confusing to a lay audience. Use of this site implies acceptance of our Terms of Use.

Cystic fibrosis transmembrane regulator

Cystic fibrosis transmembrane regulator (CFTR) is a protein encoded by the CFTR gene on chromosome 7q31.2 and is responsible for regulating chloride passage across cell membranes. It is this gene that is mutated in patients with cystic fibrosis (CF) resulting in abnormally thick secretions. There are at least 6 classes of mutations, the commonest being ∂F508. 

Updating… Please wait.
Loadinganimation

Alert_accept

Error Unable to process the form. Check for errors and try again.

Alert_accept Thank you for updating your details.