Delayed bone age
Dr Yuranga Weerakkody and Dr Hani Alsalam et al.
A generalised retardation in skeletal maturation has different causative or aetiological factors, these can be classified as follows :
-
chronic ill health
- congenital heart disease (especially cyanotic)
- chronic renal disease
- inflammatory bowel disease
- malnutrition : failure to thrive (FTT)
- rickets
- maternal deprivation
- intrauterine growth retardation (IUGR)
- infant of toxaemic mother.
-
endocrine disorders
- hypothyroidism : cretinism
- hypopituitarism with growth hormone deficiency (e.g. idiopathic, craniopharyngioma)
- hypogonadism (e.g. Turner syndrome)
- Cushing's disease
- diabetes : juvenile
- Addison disease (adrenal insufficiency) : uncommon
- hypoparathyroidism : uncommon
- chromosomal disorders
-
congenital disorders
- congenital syndromes of dwarfism or mental retardation
-
neurologic disorders
- cerebral hypoplasia
-
others : (normal variation)
- small for gestational age neonate
- idiopathic : familial short stature
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