Dilated cardiomyopathy
Dilated cardiomyopathy is defined as left ventricular chamber dilation with decreased systolic dysfunction (FEVG < 40%). There may also be right ventricular dysfunction. Causes are related to intrinsic myocardial damage.
Pathology
Dilated, thin walled, poorly contracting ventricles +/- atria
Aetiology
Although a variety of aetiologies can result in a dilated cardiomyopathy which are listed as below. Some are classified as separate entities. (See WHO 1995 classification of cardiomyopathies)
- ischaemic (coronary artery disease)
- infectious (myocarditis : virus, bacteria)
- infiltrative disease (sarcoid, amyloid)
- metabolic (uraemia, hypocalcemia, hypophosphataemia, thyrotoxicosis)
- toxic (alcohol, cocaine)
- chemotherapy (doxororubicin)
- others (peri-partum, muscular dystrophies)
- auto-immune cross reactivity (e.g. late onset cardiomyopathy in Chagas disease)
Associations
Radiographic features
Plain film
Commonly large left ventricle and atria with pulmonary oedema +/- pleural effusions
Differential diagnosis
Consider
- large pericardial effusion

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