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Dilated cardiomyopathy

Dilated cardiomyopathy is defined as left ventricular chamber dilation with decreased systolic dysfunction (FEVG < 40%). There may also be right ventricular dysfunction.  Causes are related to intrinsic myocardial damage.

Pathology

Dilated, thin walled, poorly contracting ventricles +/- atria

Aetiology

Although a variety of aetiologies can result in a dilated cardiomyopathy which are listed as below. Some are classified as separate entities. (See WHO 1995 classification of cardiomyopathies

  • ischaemic (coronary artery disease)
  • infectious (myocarditis : virus, bacteria) 
  • infiltrative disease (sarcoid, amyloid)
  • metabolic (uraemia, hypocalcemia, hypophosphataemia, thyrotoxicosis)
  • toxic (alcohol, cocaine)
  • chemotherapy (doxororubicin)
  • others (peri-partum, muscular dystrophies)
  • auto-immune cross reactivity (e.g. late onset cardiomyopathy in Chagas disease)
Associations

Radiographic features

Plain film  

Commonly large left ventricle and atria with pulmonary oedema +/- pleural effusions

Differential diagnosis

Consider
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