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Fetal intracranial calcification

Dr Abhilash Sandhyala and Radswiki et al.

Fetal intracranial calcification refers to intracranial calcification detected in utero. This can arise from a number of pathologies which include

in utero infections
- fetal toxoplasmosis infection : calcification tends to be randomly distributed
- fetal cytomegalovirus infection¹ : calcification tends to be periventricular in distribution
intracranial tumours associated with calcification : intracranial teratoma
certain phakomatoses
- Sturge-Weber syndrome
- tuberous sclerosis : rare to have calcification present in utero
sequelae of an in utero intracranial haemorrhage

Radiographic features

Antenatal ultrasound

Calcification tends to manifest as brightly echogenic foci within the fetal brain.

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