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Fetal valproate syndrome

Dr Yuranga Weerakkody et al.

The fetal valproate syndrome (FVS) is a potential embryopathy that can occur as a result from maternal intake of valproic acid (sodium valproate / Depakote) during pregnancy.

Clinical spectrum

There is a wide clinical spectrum which includes

Pathology

Many effects are thought to be due to impairment of folate metabolism

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