The Fetal Warfarin syndrome (FWS) is a rare condition which can as a result of fetal exposure to maternal ingestion of Warfarin during pregnancy
Pathology
The increased risk is at ~ 6 - 9 weeks gestation.
Clinical features
Reported clinical features include
Facial anomalies
Skeletal anomalies
Central nervous system
Cardiovascular
Differential diagnosis
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- 1. Hou JW. Fetal warfarin syndrome. Chang Gung Med J. 2004;27 (9): 691-5. - Pubmed citation
- 2. Raivio KO, Ikonen E, Saarikoski S. Fetal risks due to warfarin therapy during pregnancy. Acta Paediatr Scand. 1977;66 (6): 735-9. - Pubmed citation
- 3. Tongsong T, Wanapirak C, Piyamongkol W. Prenatal ultrasonographic findings consistent with fetal warfarin syndrome. J Ultrasound Med. 1999;18 (8): 577-80. J Ultrasound Med (citation) - Pubmed citation
- 4. Wainwright H, Beighton P. Warfarin embryopathy: fetal manifestations. Virchows Arch. 2010;457 (6): 735-9. doi:10.1007/s00428-010-0982-9 - Pubmed citation
Synonyms & Alternative Spellings
| Synonyms or Alternative Spelling |
Include in Listings? |
| Fetal Warfarin syndrome |
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| Warfarin embryopathy |
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| Warfarin fetopathy |
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| Fetal Coumadin syndrome |
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| Coumadin fetopathy |
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| Coumadin embryopathy |
✓ |