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Ground-glass opacity

Ground-glass opacification (also known as ground-glass opacity or GGO) is a hazy area of increased attenuation in the lung with preserved bronchial and vascular markings 1. Air bronchograms may be seen.

Ground-glass opacities can be caused by normal expiration, partial filling of air spaces, partial collapse of alveoli, interstitial thickening, inflammation, oedema, fibrosis, and lepidic proliferation of neoplasm.

Differential diagnosis

Broadly speaking, the differential for ground-glass opacification can be split into: 5

  • infectious processes (usually opportunistic)
  • chronic interstitial diseases
  • acute alveolar diseases
  • other causes
Opportunistic infections
Chronic interstitial diseases
Acute alveolar disease
Other causes
Rare causes

See also

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