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Hepatoblastoma histological classification

Dr Frank Gaillard et al.

Although hepatoblastomas can be histologically classified into a variety of sub types, it is important to remember that with the possible exception of small cell undifferentiated sub type, prognosis is independent of histology when adjusted for stage gender and age 1.

  • major categories
    • epithelial
      • foetal, well differentiated
      • embryonal
      • macrotrabecular
    • mixed
    • small cell undifferentiated
    • rhabdoid
  • minor categories
    • cholangioblastic (ductal)
    • keratinising squamous epithelium
    • intestinal glandular epithelium
    • teratoid (neuroid-melanocytic)
    • rhabdomyoblastic
    • chondroid
    • osteoid

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