The hummingbird sign, also known as the penguin sign, refers to the appearance of the brainstem in patients with progressive supranuclear palsy (PSP). The atrophy of the midbrain results in a profile of the brainstem in which the persevered pons forms the body of the bird, and the atrophic midbrain the head, with beak extending anteriorly towards the optic chiasm.
- 1. Gröschel K, Kastrup A, Litvan I et-al. Penguins and hummingbirds: midbrain atrophy in progressive supranuclear palsy. Neurology. 2006;66 (6): 949-50. doi:10.1212/01.wnl.0000203342.77115.bf - Pubmed citation
- 2. Shukla R, Sinha M, Kumar R et-al. 'Hummingbird' sign in progressive supranuclear palsy. Ann Indian Acad Neurol. 2009;12 (2): 133. doi:10.4103/0972-2327.53087 - Free text at pubmed - Pubmed citation
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