Hyperparathyroidism

Hyperparathyroidism is the effect of excess parathyroid hormone (PTH) in the body. It can be primary, secondary or tertiary. There are many characteristic imaging features predominantly involving the skeletal system.

Pathology

Increased levels of the PTH lead to increased osteoclastic activity. The resultant bone resorption produces cortical thinning (subperiosteal resorption) and osteopaenia.

Subtypes
Associations

Hyperparathyroidism can occur in the context of the following conditions from parathyroid hyperplasia or less commonly multiple parathyroid adenomas 5:

Radiographic features

Findings in secondary (and tertiary) hyperparathyroidism are often associated with the osteosclerosis of renal osteodystrophy, and the osteomalacia of vitamin D deficiency:


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