An incisive canal cyst (or nasopalatine duct cyst (NPDC)) is a developmental cyst non neoplastic cyst arising from degeneration of nasopalatine ducts. These ducts usually regress in fetal life. The persistence of ductal epithelium leads to formation of cyst.
It is considered the most common non-odontogenic cyst and develops only in the midline anterior maxilla.
They most commonly occur in 4th to 6th decades, have a male predominance and affect about 1% of the population.
Most patients are symptomatic. They present as swelling of anterior palate, sometimes associated with pain and drainage. They must usually be larger than 0.6cm to distinguish cyst from incisive foramen, which is a normal anatomical feature.
Cyst formation is due to spontaneous cystic degeneration of residual ductal epithelium. The vast majority of cases contain non-keratinized stratified squamous epithelium alone or in combination with other epithelia histologically. Approximately 30% cases contain repiratory epithelium 3.
They are seen as a solitary well-defined, oval or round unilocular radiolucency, between central incisors, > 0.6 cm in diameter. They may appear “heart-shaped” if the anterior nasal spine superimposed. Root resorption and tooth displacement may be present.
Usually shows homogeneous high signal intensity on both on T1 and T2, although most cysts of maxillofacial regions demonstrate low to intermediate signal intensity on T1 weighted images 1.
Treatment and prognosis
Enucleation is usually curative, and recurrence is rare. Histological confirmation is recommended.
General imaging differential considerations include
- periapical granuloma / periapical cyst
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- 1. Hisatomi M, Asaumi J, Konouchi H et-al. MR imaging of nasopalatine duct cysts. Eur J Radiol. 2001;39 (2): 73-6. Eur J Radiol (link) - Pubmed citation
- 2. Elliott KA, Franzese CB, Pitman KT. Diagnosis and surgical management of nasopalatine duct cysts. Laryngoscope. 2004;114 (8): 1336-40. doi:10.1097/00005537-200408000-00004 - Pubmed citation
- 3. Swanson KS, Kaugars GE, Gunsolley JC. Nasopalatine duct cyst: an analysis of 334 cases. J. Oral Maxillofac. Surg. 1991;49 (3): 268-71. J. Oral Maxillofac. Surg. (link) - Pubmed citation
- 4. Vasconcelos R, De aguiar MF, Castro W et-al. Retrospective analysis of 31 cases of nasopalatine duct cyst. Oral Dis. 1999;5 (4): 325-8. - Pubmed citation
Synonyms & Alternative Spellings
|Synonyms or Alternative Spelling||Include in Listings?|
|Nasopalatine duct cyst||✓|
|Incisive canal cysts||✗|
|Nasopalatine duct cysts||✗|
|Nasopalatine duct cyst (NPDC)||✗|