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Lady Windermere syndrome

Radswiki and Dr Frank Gaillard et al.

The Lady Windermere syndrome refers to a pattern of pulmonary Mycobacterium avium complex (MAC) infection seen typically in elderly white women who chronically suppress the normal cough reflex. A fastidious nature and a reticence to expectorate are believed to predispose such persons to infections with MAC.

Typical manifestation is of bronchiectasis, centrilobular nodules and eventual scarring and volume loss affecting the right middle lobe and left lingula 1. 

It is one of the causes of right middle lobe syndrome. 

Etymology

The syndrome is named after Lady Windermere, a character in Oscar Wilde's 1892 play Lady Windermere's fan 2.

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