Lady Windermere syndrome

Last revised by Yuranga Weerakkody on 16 Jan 2024

Citation, DOI, disclosures and article data

Citation:

Gaillard F, Weerakkody Y, Elfeky M, et al. Lady Windermere syndrome. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-9281

DOI:

https://doi.org/10.53347/rID-9281

Permalink:

https://radiopaedia.org/articles/9281

rID:

9281

Article created:

28 Mar 2010, Frank Gaillard ◉ ◈

Disclosures:

At the time the article was created Frank Gaillard had no recorded disclosures.

View Frank Gaillard's current disclosures

Last revised:

16 Jan 2024, Yuranga Weerakkody ◉

Disclosures:

At the time the article was last revised Yuranga Weerakkody had no financial relationships to ineligible companies to disclose.

View Yuranga Weerakkody's current disclosures

Revisions:

11 times, by 9 contributors - see full revision history and disclosures

Systems:

Chest

Sections:

Syndromes

Tags:

syndrome

Synonyms:

Lady Windermere's syndrome

Lady Windermere syndrome refers to a pattern of pulmonary Mycobacterium avium complex (MAC) infection seen typically in elderly white women who chronically suppress the normal cough reflex. A fastidious nature and a reticence to expectorate are believed to predispose such persons to infections with MAC.

Radiographic features

Plain radiograph

Linear opacities in middle lobe or lingula can be seen, as a result of subsegmental atelectasis or bronchiectasis with mucosal impactions. Residual middle lobe or lingula atelectasis can also be seen.

CT

Typical manifestation is of bronchiectasis, centrilobular nodules, tree-in-bud nodularity and eventual scarring and volume loss affecting the middle lobe and lingula ¹.

It is one of the causes of right middle lobe syndrome.

History and etymology

The syndrome is named after Lady Windermere, a character in Oscar Wilde's 1892 play 'Lady Windermere's Fan' ².

References

Incoming Links

Promoted articles (advertising)

ADVERTISEMENT: Supporters see fewer/no ads

{"current_user":null,"inclusions":[{"imageId":54277932,"studyId":102195,"caseSlug":"lady-windermere-syndrome-1","caption":"Case 1: x-ray","thumbnail":"https://prod-images-static.radiopaedia.org/images/54277932/AP_big_gallery.jpeg","isStack":false,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":54278048,"studyId":102196,"caseSlug":"lady-windermere-syndrome-1","caption":"Case 1: CT","thumbnail":"https://prod-images-static.radiopaedia.org/images/54278048/781bb8493a69178f524dc58c36a4c997800f428e2c0a2f06c87ce264beb6c2fd_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":382195,"studyId":9937,"caseSlug":"right-middle-lobe-bronchiectasis-mycobacterium-avium-complex","caption":"Case 2","thumbnail":"https://prod-images-static.radiopaedia.org/images/382195/9a6ea3d09954c6822f708dead19ea1_big_gallery.jpg","isStack":true,"diagnosticCertainty":"probable"},{"imageId":1324199,"studyId":14558,"caseSlug":"cystic-bronchiectasis-2","caption":"Case 3","thumbnail":"https://prod-images-static.radiopaedia.org/images/1324199/88ac97dfbe5150162802ec2980f993_big_gallery.jpg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":15676246,"studyId":41742,"caseSlug":"lady-windermere-syndrome","caption":"Case 4","thumbnail":"https://prod-images-static.radiopaedia.org/images/15676246/106c23e125112e86d91681cec94a9c_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"},{"imageId":21670515,"studyId":48291,"caseSlug":"pulmonary-mycobacterium-avium-complex-infection-1","caption":"Case 5","thumbnail":"https://prod-images-static.radiopaedia.org/images/21670515/630256a05bf32a5793777219f74312_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"},{"imageId":29010180,"studyId":57487,"caseSlug":"right-middle-lobe-bronchiectasis-1","caption":"Case 6","thumbnail":"https://prod-images-static.radiopaedia.org/images/29010180/3fe9e25db9813f3514d211a8c532d1_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"},{"imageId":64299728,"studyId":144944,"caseSlug":"lady-windermere-syndrome-7","caption":"Case 7","thumbnail":"https://prod-images-static.radiopaedia.org/images/64299728/a37e5842777be22f2989b4ad086ab0fe953b614b1caf583195a839f4f9240c2b_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"}],"ddx_inclusions":[],"lang":"us"}