Leontiasis ossea
Leontiasis ossea is a largely historical term used to describe a number of conditions which result in the affected patient's face resembling that of a lion. Although it is most frequently associated with craniofacial fibrous dysplasia, it has a broader meaning encompassing other lesions that have similar appearance 1,4.
In general the distinction is made between true leontiasis ossea (craniofacial fibrous dysplasia) and other conditions having similar external appearance (mimics), however it would be safe to say that as a term it is no longer of clinical use and should be avoided.
In addition to craniofacial fibrous dysplasia the following conditions may mimic leontiasis ossea:
- Paget disease
- gigantism
- craniosysonstosis
- tumours of the paranasal sinuses
- syphilitic osteoperiostitis
- ureamia with secondary hyperparathyroidism 2
Etymology
The famed Virchow first coined the term leontiasis ossea in 1864 3.
- Rudolf Ludwig Karl Virchow : (1821 - 1902) German pathologist and statesman 5

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