Leontiasis ossea is a largely historical term used to describe a number of conditions which result in the affected patient's face resembling that of a lion. Although it is most frequently associated with craniofacial fibrous dysplasia, it has a broader meaning encompassing other lesions that have similar appearance 1,4.
In general the distinction is made between true leontiasis ossea (craniofacial fibrous dysplasia) and other conditions having similar external appearance (mimics), however it would be safe to say that as a term it is no longer of clinical use and should be avoided.
In addition to craniofacial fibrous dysplasia the following conditions may mimic leontiasis ossea:
- Paget disease
- tumours of the paranasal sinuses
- syphilitic osteoperiostitis
- ureamia with secondary hyperparathyroidism 2
The famed Virchow first coined the term leontiasis ossea in 1864 3.
- Rudolf Ludwig Karl Virchow : (1821 - 1902) German pathologist and statesman 5
- 1. EVANS J. “Leontiasis ossea; a critical review, with reports of four original cases.” The Journal of Bone and Joint Surgery. British Volume 35-B, no. 2 (May 1953): 229-243.
- 2. Maramattom Boby. “Leontiasis ossea and post traumatic cervical cord contusion in polyostotic fibrous dysplasia.” Head & Face Medicine 2, no. 1 (2006): 24. doi:10.1186/1746-160X-2-24.
- 3. Capon, Norman B. "A Case of Leontiasis Ossea (Diffuse Osteitic Form)" Arch Dis Child 1928 3: 285-291
- 4. Classic Radiologic Signs: An Atlas and History. M.E. Mulligan. Informa Healthcare; 1st edition (November 15, 1996)
- 5. Rudolf Ludwig Karl Virchow from whonamedit.com, the dictionary of medical eponyms. Rudolf Ludwig Karl Virchow