Simple pulmonary eosinophilia (also known as Löffler syndrome) is an idopathic type of pulmonary eosinophilia. It typically presents with transient radiographic infiltrates, minimal constitutional upset and an elevated eosinophil count in peripheral blood.
Plain film (CXR) / HRCT
There is often a fleeting type transient non segmental air space opacification which may be unilateral or bilateral. Usually has predominantly peripheral distribution. Pleural effusions and lymphadenopathy is not a feature.
A restrictive type cardiomyopathy can develop from endomyocardial fibrosis
Treatment and prognosis
Treatment if usually not required and opacities resolve within a month 3,5.
Named after Wilhelm Löffler : Swiss physician ( 1887- 1972) who first described the case histories of patients with chest radiographic infiltrates in 1932.
- 1. Grainger RG, Allison DJ. Grainger and Allison's diagnostic radiology, a textbook of medical imaging. Churchill Livingstone. (2001) ISBN:0443064326. Read it at Google Books - Find it at Amazon
- 2. Wilhelm Löffler from whonamedit.com, the dictionary of medical eponyms. Wilhelm Löffler
- 3. Jeong YJ, Kim KI, Seo IJ et-al. Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview. Radiographics. 27 (3): 617-37. doi:10.1148/rg.273065051 - Pubmed citation
- 4. Johkoh T, Müller NL, Akira M et-al. Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients. Radiology. 2000;216 (3): 773-80. Radiology (full text) - Pubmed citation
Synonyms & Alternative Spellings
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|Simple pulmonary eosinophilia||✗|