Mandibular lesions
The mandible, due to the presence of teeth, is the site of many lesions that are unique to it (shared with the maxilla of course). Lesions can therefore be odontogenic and non-odontogenic, and although it may often not be possible to make a diagnosis on imaging alone, the differential can be narrowed. Although a histological classification is probably the most scientifically sound, as radiologists we are presented with an image, and therefore it is easier to classify lesions according to location in the mandible and appearance. (for a detailed classification of odontogenic tumours, many more than even the keenest neuro / head and neck radiologist can ever remember, please refer to the WHO classification scheme for odontogenic tumours (1992).
Below the lesions are divided into Cystic and Solid. Cystic should not be confused with lytic as solid radiolucent lesions can also appear lytic... (see lytic lesions of the jaw)
Cystic lesions
- periapical cyst (or radicular cyst) : common
- follicular cyst of the mandible (or dentigerous cyst) : common
- odontogenic keratocyst (OKC) : uncommon
- primordial cyst of the mandible
- Stafne cyst (or static bone cavity) : uncommon
- solitary bone cyst of the mandible (or traumatic or haemorraghic bone cysts)
- aneursymal bone cyst (ABC) : rare in the mandible
- residual cyst of the mandible
Benign Solid lesions
Odontogenic
- odontoma : common
- ameloblastoma : relatively common
- odontogenic myxoma (looks just like an ameloblastoma) : rare
- calcifying epithelial odontogenic tumour (or Pindborg tumour) (looks just like an ameloblastoma) : rare
- cementoblastoma : rare
- ameloblastic fibroma
- adenomatoid odontogenic tumour : rare
Non odontogenic
- cemento-ossifying fibroma
- juvenile ossifying fibroma
- exostosis (or torus mandibularis)
- osteoma
- fibrous dysplasia
- Paget's disease
- neurofibroma
- schwannoma
- central giant cell granuloma (giant cell reparative cyst)
Malignant Solid lesions
Odontogenic
- odontogenic carcinoma (e.g ameloblastic carcinoma) : rare
- odontogenic sarcoma : rare
- odontogenic carcinosarcoma : rare
Non odontogenic
- osteosarcoma
- chondrosarcoma
- metastasis
- fibrosarcoma
- leiomyosarcoma
- lymphoma / leukemia
- multiple myeloma / plasmacytoma
- squamous cell carcinoma of mandible : common

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