Microphthalmia

Last revised by Mostafa Elfeky on 31 Aug 2021

Microphthalmia essentially means small eyes. It is characterized by a small eye within a small orbit. It can be unilateral or bilateral. It is sometimes defined as a globe with a total axial length that is at least two standard deviations below the mean for age.

Microphthalmia can have a complex etiology and genetics.

Microphthalmia can either occur isolation in association or with numerous other conditions which include

Assessment and detection of microphthalmia antenatally is difficult and is often inferred from a small size of the orbit. There may or may not be evidence of concurrent hypotelorism.

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