Midaortic syndrome (MAS) is an uncommon entity affecting children and young adults. It is characterised by progressive narrowing of abdominal aorta and its major branches1.
The onset of symptoms is usually during young adulthood or childhood2.
- hypertension (most common)
- intermittent claudication
- renal failure
The exact cause is unknown though it is probably due to an insult during intrauterine life. Whilst intimal and subintimal fibrosis and fragmentation of the elastic media are seen, arteritis and atherosclerosis are characteristically absent in this condition.
DSA - Angiography
Whilst involvement of any portion of the abdominal aorta may been seen, the interrenal segment including the origins of the renal arteries is invariably narrowed. Typically enlarged splanchnic collaterals (IMA, arc of Riolan, marginal artery of Drummond) are noted. The aortic bifurcation and iliac arteries are spared3.
- 1. Cura MA, Bugnone A, Becker GJ. Midaortic syndrome associated with fetal alcohol syndrome. J Vasc Interv Radiol. 2002;13 (11): 1167-70. - Pubmed citation
- 2. Sumboonnanonda A, Robinson BL, Gedroyc WM et-al. Middle aortic syndrome: clinical and radiological findings. Arch. Dis. Child. 1992;67 (4): 501-5. Arch. Dis. Child. (citation) - Free text at pubmed - Pubmed citation
- 3. Lewis VD, Meranze SG, Mclean GK et-al. The midaortic syndrome: diagnosis and treatment. Radiology. 1988;167 (1): 111-3. Radiology (citation) - Pubmed citation
Synonyms & Alternative Spellings
|Synonyms or Alternative Spelling||Include in Listings?|
|Abdominal aortic coarctation||✓|