Müllerian duct anomalies (MDAs) are congenital abnormalities that occur when the Müllerian ducts (paramesonephric ducts) do not develop correctly. This may be as a result of complete agenesis, defective vertical or lateral fusion, or resorption failure.
Despite these anomalies being common 1, the majority are asymptomatic. The Müllerian duct anomaly classification system divides them according to clinical manifestations, prognosis, and treatment. Accurate diagnosis is essential, since management varies according to the type of malformation.
Obstruction of the Müllerian duct may occur : patients present with an abdominal mass and dysmenorrhea. Delayed treatment may result in severe consequences and potentially infertility.
Renal anomalies are frequently associated
- uterine agenesis : ~ 10 %
- arcuate uterus : often considered as part of normal anatomical variation : ~ 7 %
- unicornuate uterus : ~ 5 - 25 %
- uterine duplicational anomalies
- should be performed initially
- confirms any structural abnormalities of the genital tract
- sometimes cannot help to identify the type of MDA
- valuable non invasive technique
- evaluation of the female pelvic anatomy
- accurate MDA classification
Treatment and prognosis
Many patients are asymptomatic and require no treatment. However, where obstruction occurs, surgical intervention is usually required and may result in permanent infertility : counseling is required.
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- 1. Junqueira BL, Allen LM, Spitzer RF et-al. Müllerian duct anomalies and mimics in children and adolescents: correlative intraoperative assessment with clinical imaging. Radiographics. 29 (4): 1085-103. doi:10.1148/rg.294085737 - Pubmed citation
- 2. Troiano RN, Mccarthy SM. Mullerian duct anomalies: imaging and clinical issues. Radiology. 2004;233 (1): 19-34. doi:10.1148/radiol.2331020777 - Pubmed citation
- 3. Steinkeler JA, Woodfield CA, Lazarus E et-al. Female infertility: a systematic approach to radiologic imaging and diagnosis. Radiographics. 29 (5): 1353-70. doi:10.1148/rg.295095047 - Pubmed citation
- 4. Saleem SN. MR imaging diagnosis of uterovaginal anomalies: current state of the art. Radiographics. 23 (5): e13. doi:10.1148/rg.e13 - Pubmed citation
Synonyms & Alternative Spellings
|Synonyms or Alternative Spelling||Include in Listings?|
|Müllerian duct anomaly (MDA)||✗|
|Mullerian duct anomaly||✗|
|Anomalies of uterine development||✗|
|Congenital uterine anomalies||✗|