Multiple endocrine neoplasia type IIb
Dr Jeremy Jones and Dr Frank Gaillard et al.
Multiple endocrine neoplasia (MEN) type IIb (also known as mucosal neuroma syndrome3) accounts for only 5% cases of MEN II and is characterised by:
- pheochromocytoma(s) : in 50% of patients, often bilateral, and can be extra-adrenal
- medullary thyroid cancer : 100% of patients ; aggressive, and may elaborate calcitonin.
- mucosal neuroma(s) / ganglioneuroma(s)
- marfanoid habitus
Mnemonic : PMMM

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