Neuritic plaques (also known as senile plaques) are a feature of Alzheimer's disease. They are extracellular and composed of a central core of beta-amyloid peptides aggregated together with fibrils of beta-amyloid, dystrophic neurites, reactive astrocytes, phagocytic cells, and other proteins and protein fragments derived from degenerating cells or liberated from neurons 1.
They should not be confused with neurofibrillary tangles which are intracytoplasmic.
Synonyms & Alternative Spellings
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