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Pancreatic lipomatosis

Pancreatic lipomatosis refers to fatty replacement of pancreatic parenchyma. This finding is most often associated with obesity and aging. 

It tends to be commonest pathological condition involving the pancreas. The condition may occassionally simulate a mass like lesion particularly situation where fatty replacement is uneven 1

Pathology

Sub types
  • even pancreatic lipomatosis
  • uneven pancreatic lipomatosis 3
    • type 1a: preferential fatty replacement of head
    • type 1b: preferential fatty replacement of head, neck and body
    • type 2a: preferential fatty replacement of head and uncinate process
    • type 2b: fatty replacement of most of pancreas except peribiliary region
Causes
Systemic
Local
Syndromic associations

Differential diagnosis

Imaging differential considerations include:

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