Parotid enlargement
Parotid enlargement has a wide differential given the significant breadth of pathology that can affect the parotid gland. These can be separated by the standard surgical sieve approach into infective, inflammatory, immune, neoplastic, infiltrative and congenital causes.
Classification
Infection
- mumps
- tuberculosis
- cat-scratch fever
- syphilis
- parotid abscess secondary to acute bacterial sialadenitis (acute parotitis)
- HIV parotitis
Inflammatory
- chronic recurrent sialadenitis
- sarcoidosis
- benign lymphoepithelial lesions
Immune mediated
- Sjogren syndrome (myoepithelial sialadenitis)
- Mikulicz syndrome
Miscellaneous
Neoplastic
See also : salivary gland tumours
-
benign
- pleomorphic adenoma
- Warthin tumour (commonest bilateral tumour)
- parotid lipoma
- benign lymphoepithelial lesions (may be multiple and bilateral)
- facial nerve neurofibroma
- parotid oncocytoma
- parotid haemangioma
- angiolipoma
- malignant primary tumour
-
metastatic
- squamous cell carcinoma
- melanoma of periauricular region
- thyroid carcinoma
-
lymphoproliferative
- lymphoma
- leukaemia
- primary NHL (MALToma)

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