Plasma cell mastitis

Dr Henry Knipe and Radswiki et al.

Plasma cell mastitis is a benign breast condition which represents calcification of inspissated secretions in or immediately adjacent to ectatic benign ducts. 

Epidemiology

It is typically seen in older women (e.g. > 60 years of age).

Pathology

It is thought to represent aseptic inflammation of the breast from extravasation of intraductal secretions into periductal connective tissue. 

Radiographic features

Mammography

Plasma cell mastitis has a characteristic appearance. Calcifications are thick, linear, rod-like or cigar-shaped. Calcifications can be up to 10 mm long. They tend to be bilateral, often symmetrical in distribution and oriented with long axes pointing toward the nipple1. Branching may sometimes be seen. 

Compared to microcalcifications of DCIS or ductal carcinoma, calcifications of plasma cell mastitis are larger in both length and caliber and have a smoother outline. 

Treatment and prognosis

It is a benign entity and there no increased risk of malignancy 3.


Breast imaging and pathology
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Article Information:

rID: 12476
System: Breast
Section: Pathology
Synonyms or Alternate Spellings:
  • Secretory disease of the breast
  • Secreatory breast disease
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    Case 1
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    Case 2: with associated fibroadenomas
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    Case 3
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