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Primary urethral cancer staging

Dr Ayush Goel and Radswiki et al.

Primary urethral cancer staging often uses the TNM system and is as follows:

  • T: primary tumour
    • Tx: primary tumour cannot be assessed
    • T0: no evidence of primary tumour
    • Tis: carcinoma in situ
    • Ta: non-invasive papillary, polypoid, or verrucous carcinoma
    • T1: invasion of sub epithelial connective tissue
    • T2: invasion of corpus spongiosum/prostate or peri urethral muscles
    • T3: corpus cavernosum, beyond prostate capsule, anterior vagina, bladder neck
    • T4: invasion of adjacent organs
  • N: nodal status
    • Nx: nodal status cannot be assessed
    • N0: no nodal involvement
    • N1: single nodal metastasis <2cm in greatest dimension
    • N2: single node more than 2 cm in greatest dimension or multiple nodes
  • M: distant metastases
    • Mx: distant metastatic disease cannot be assessed
    • M0: no distant metastases
    • M1: distant metastases present

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