Pulmonary lymphoma
Dr Yuranga Weerakkody et al.
Pulmonary lymphoma refers to lung parenchymal involvement with lymphoma.
It can be broadly divided as primary or secondary.
-
primary pulmonary lymphoma - (rare) usually non-Hodgkin lymphoma which is limited to the lung with or without mediastinal lymph node involvement and with no evidence of extrathoracic dissemination for at least 3 months after the initial diagnosis.
- low-grade B-cell lymphoma (baltoma) : commonest ~ 80% of primary pulmonary lymphoma
- high grade lymphoma : most commonly B-cell, occasionally anaplastic and peripheral T-cell types
- angiocentric immunoproliferative lesion (lymphomatoid granulomatosis)
- secondary pulmonary lymphoma - relatively common
Two additional categories have also been described which include 4
- lymphoma in patients with post-transplant lymphoprohiferative disorders (PTLD)
- AIDS-related pulmonary lymphoma (ARL - ARPL)
Radiographic features
HRCT - chest
A number of features may be present on HRCT which include
- a mass or mass-like consolidation greater than 1 cm with or without cavitations or bronchograms : most common finding according to one study 2
- nodules less than 1 cm
- alveolar or interstitial infiltrates
- masses of pleural origin
- peribronchial or perivascular thickening with or without atelectasis
- pleural effusions
- hilar or mediastinal lymphadenopathy
See also
- pulmonary pseudolymphoma - benign inflammatory lymphocytic infiltrate of the lungs
- pulmonary manifestations of Hodgkin lymphoma
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