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Renal haemosiderosis

Renal hemosiderosis results from accumulation of hemosiderin in the kidneys.

Renal haemosiderosis is a known complication of the following conditions:

  • chronic intravascular hemolytic states such as haemolytic anaemias like sickle cell anemia and thalassemia 1,3
  • paroxysmal nocturnal hemoglobinuria (PNH)
  • mechanical hemolysis from prosthetic cardiac valve 

Radiographic features

CT

No focal abnormalities usually seen on CT.

MRI

The kidneys exhibit abnormally low renal cortical signal in T1W and T2W sequences on MRI.

Differential diagnosis

General imaging differential considerations include

Significance

Usually considered a benign and incidental radiologic finding and rarely results in clinically apparent renal dysfunction. 

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