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Renal osteodystrophy

Renal osteodystrophy (ROD), also known as uraemic osteopathy, is the constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed:

Radiographic features

Imaging findings are many and varied:

  • osteopaenia: (often seen early) thinning of cortices and trabeculae
  • salt and pepper skull
  • demineralization: usually subperiosteal, however it may also involve joint margins, endosteal, subchondral, subligamentous areas, cortical bone or trabeculae 5 
  • subperiosteal resorption: characteristic subperiosteal resorption may be seen on radial aspects of middle phalanges of index and long fingers.
  • bone sclerosis ​ ​
  • soft tissue calcification
  • amyloid deposition: erosion in and around joint
  • insufficiency fractures
  • Looser's zone
  • Brown tumours

Differential diagnosis

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