Retroperiotoneal liposarcoma is a sub type of liposarcoma, a malignant tumour of mesenchymal origin that may arise in any fat-containing region of the body. It is one of the most common primary retroperitoneal neoplasms 2.
There are five histological types:
- well-differentiated: ~54%, low grade
- myxoid: ~31%, low to intermediate grade
- pleomarphic: high grade
- round cell: high grade
- dedifferentiated: high grade
Metastatic disease is haematogenous and the extent of metastases is related to the histological grade of the tumour.
- heterogenous mass
- varying amount of fat and soft tissue
- multiple septae
- enhancing soft tissue components
- myxoid: hyperintense on T2WI with delayed post-contrast enhancement
The primary treatment option if resection if possible. However, local recurrence is common and occurs in 2/3 of patients. This is usually a sign of imcomplete resection and highlights the difficulty in discriminating liposarcomas from normal retroperitoneal fat.
- 1. Nishino M, Hayakawa K, Minami M et-al. Primary retroperitoneal neoplasms: CT and MR imaging findings with anatomic and pathologic diagnostic clues. Radiographics. 23 (1): 45-57. doi:10.1148/rg.231025037 - Pubmed citation
- 2. Craig WD, Fanburg-Smith JC, Henry LR et-al. Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics. 2009;29 (1): 261-90. Radiographics (full text) - doi:10.1148/rg.291085203 - Pubmed citation
Synonyms & Alternative Spellings
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|Liposarcoma of retroperitoneum||✗|